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Articles tagged ‘vitamin K antagonists’

January 29, 2015

Meta-analysis confirms less bleeding risk with new oral anticoagulants

When compared with vitamin K antagonists (VKAs) administered to a target INR of 2.0 to 3.0, target-specific oral anticoagulants (TSOACs) are associated with less major bleeding, fatal bleeding, intracranial bleeding, clinically relevant non-major bleeding, and total bleeding, according to a study published recently in Blood.1

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December 19, 2014

Lower bleeding risk with apixaban versus VKAs

Apixaban is associated with a lower risk of bleeding than vitamin K antagonists (VKAs), which provides some reassurance regarding its safety, according to the authors of a meta-analysis published recently in the American Journal of Cardiology.1

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August 5, 2014

Apixaban versus warfarin and aspirin: results from AVERROES and ARISTOTLE

The efficacy and safety of apixaban compared with aspirin are consistent in subgroups of patients who have previously attempted but failed Vitamin K antagonist (VKA) therapy, irrespective of the reason for discontinuation, according to a study published recently in the European Heart Journal.1

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May 24, 2012

New oral anticoagulants stake their claim

“New oral anticoagulants are poised to replace vitamin K antagonists for many patients with atrial fibrillation, and may have a role after acute coronary syndromes,” according to a review published recently in the Journal of the American College of Cardiology.1

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  • ArrhythmiaAlliance
  • Stars
  • Anticoagulation Europe
  • Atrial Fibrillation Association

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