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Articles tagged ‘factor Xa inhibitor’

December 19, 2014

Lower bleeding risk with apixaban versus VKAs

Apixaban is associated with a lower risk of bleeding than vitamin K antagonists (VKAs), which provides some reassurance regarding its safety, according to the authors of a meta-analysis published recently in the American Journal of Cardiology.1

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March 28, 2014

ARISTOTLE: new analysis shows less bleeding and strokes with apixaban

The novel oral anticoagulant apixaban is associated with fewer intracranial haemorrhages compared with warfarin, as well as less adverse consequences following extracranial haemorrhage, according to a study published recently in the Journal of the American College of Cardiology.1 The study also showed a 50% reduction in fatal consequences at 30 days in cases of major haemorrhage with apixaban.

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December 20, 2013

Apixaban unaffected by patient ethnicity

Apixaban was safe and well-tolerated in healthy Chinese subjects, with pharmacokinetics (PK), and pharmacodynamics (PD) predictable and consistent with findings from previous studies in Asian and non-Asian subjects, according to a study1 published recently in Clinical Pharmacology: Advances and Applications.

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November 20, 2013

Apixaban as good as warfarin after cardioversion

Major cardiovascular events after cardioversion of atrial fibrillation (AF) are rare and comparable between warfarin and apixaban, according to a study1 published recently in the Journal of the American College of Cardiology.

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April 26, 2013

Apixaban unaffected by gastric acid suppressant

Histamine H2-receptor antagonist famotidine does not affect the pharmacokinetics of apixaban in healthy subjects, suggesting that apixaban can be administered without regard to coadministration of gastric acid modifiers, according to a study1 published recently in Clinical Pharmacology: Advances and Applications.

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December 20, 2012

Bleeding similarities between aspirin and apixaban

Anatomic sites and predictors of bleeding are similar for apixaban and aspirin in patients with atrial fibrillation (AF) who are unsuitable for vitamin K antagonist therapy, according to a study1 published recently in Stroke.

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ENDORSED BY

  • ArrhythmiaAlliance
  • Stars
  • Anticoagulation Europe
  • Atrial Fibrillation Association
 

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