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December 19, 2014

Lower bleeding risk with apixaban versus VKAs

Apixaban is associated with a lower risk of bleeding than vitamin K antagonists (VKAs), which provides some reassurance regarding its safety, according to the authors of a meta-analysis published recently in the American Journal of Cardiology.1

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December 19, 2014

Type 2 diabetes “reversible” with lifestyle changes

Early type 2 diabetes can be reversed with lifestyle changes, according to European Society of Cardiology (ESC) spokesperson Professor Eberhard Standl (Munich Diabetes Research Group, Germany) in a recent statement accompanying this year’s World Diabetes Day.

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December 19, 2014

Direct and indirect costs of stroke associated with AF

Stroke associated with atrial fibrillation (AF-stroke) is associated with substantially higher total, acute hospital, nursing home, and general practitioner costs per patient, according to a study published recently in Stroke.1

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December 19, 2014

Antithrombotic therapy after acute ischaemic stroke in patients with AF

Contrary to current guidelines, 30% of patients with atrial fibrillation (AF) and recent ischaemic stroke (IS) are not prescribed any oral anticoagulation (OAC) therapy on discharge, whereas a further 30% are prescribed combination OAC and antiplatelet therapy, according to a study published recently in Stroke.1

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December 19, 2014

AF-related strokes on increase, despite more anticoagulation

Numbers of atrial fibrillation (AF)-related incident ischaemic strokes at age ≥80 years have trebled over the last 25 years, despite the introduction of anticoagulants, and are projected to treble again by 2050, along with the numbers of systemic emboli, according to a study published recently in Circulation.1

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December 19, 2014

Digoxin can increase risk of death in AF

In adults with atrial fibrillation (AF), digoxin use is independently associated with higher risks of death and hospitalisation, according to a study published recently in Circulation: Arrhythmia and Electrophysiology.1

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December 19, 2014

AF recurrence unaffected by n-3 PUFAs treatment

In patients with paroxysmal or persistent atrial fibrillation (AF), treatment with omega-3 polyunsaturated fatty acids (n-3 PUFAs) does not reduce the recurrence of AF, nor does it affect concentrations of markers for inflammation and oxidative stress, according to a study published online recently by the American Journal of Cardiology.1

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December 19, 2014

New European atlas on the prevention of AF-related stroke launched

The burden of atrial fibrillation (AF)-related stroke prevention in different countries across Europe is shown by a comprehensive new report – ‘The Route Map for Change and European Atlas on the Prevention of AF-related Stroke’ – released recently the Arrhythmia Alliance.

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December 19, 2014

Moderate sleep restriction impairs endothelial function…

Partial sleep restriction were found to cause endothelial dysfunction in healthy individuals, implicating it as a possible mediator of the heightened cardiovascular risk associated with short sleep duration, according to a study published recently in the Journal of the American Heart Association.1

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December 19, 2014

PROTECT AF – percutaneous LAA closure superior to warfarin

Percutaneous left atrial appendage (LAA) closure is superior to warfarin for preventing the combined outcome of stroke, systemic embolism, and cardiovascular death, as well as for cardiovascular and all-cause mortality, in patients with non-valvular atrial fibrillation (AF) at elevated risk for stroke, according to results form the PROTECT AF trial published recently in the Journal of the American Medical Association.1

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