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New guide highlights diverse drug targets

The new Concise Guide to Pharmacology 2015/20161 provides a valuable and unique overview of the key properties of more than 1,700 human drug targets, focusing on those exploited currently in the clinic or with future therapeutic potential.

The Guide, which is published every two years and is freely available online, is a snapshot of information collected by the Nomenclature Committee of the International Union of Basic and Clinical Pharmacology, a voluntary, non-profit association of pharmacology societies representing the interests of pharmacologists world-wide.

“This update is a state-of-the-art reference guide to the key pharmacological and therapeutic targets of drugs. It combines an evidence base of quantitative pharmacological data with focused summaries of families of receptors, ion channels, transporters, and enzymes, allowing anyone new to the field to gain a rapid insight into their function and comparative pharmacology,” said Dr Stephen Alexander, corresponding author of the Guide, which is published as a special issue in the British Journal of Pharmacology.

“It also interfaces with the online GuidetoPHARMACOLOGY.org, with more detailed information on the majority of molecular targets of drugs, as well as allowing rapid navigation to multiple online databases of genetic, therapeutic, molecular biological, immunological and chemical properties,” Dr Alexander added.

References

1. Alexander SPH, Kelly E, Marrion N, et al. The Concise Guide to PHARMACOLOGY 2015/16. British Journal of Pharmacology 2015;172:5729–6202. http://dx.doi.org/10.1111/bph.13347

Published on: January 14, 2016

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