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Results from world’s largest study on stroke risk factors

The association between 10 known risk factors and roughly 90% of strokes has been shown in large patient populations, according to preliminary findings from the INTERSTROKE study presented recently at the World Heart Federation’s World Congress of Cardiology. The results also demonstrate an overall consistency in the collective importance of these risk factors around the world, say the authors.

INTERSTROKE is the largest international study ever to evaluate the importance of both established and novel risk factors for stroke. Completed in March 2014, the much anticipated study led by Dr Martin O’Donnell (Population Health Research Institute, McMaster University and HRB-Clinical Research Facility, NUI Galway, Ireland) and Dr Salim Yusuf (Population Health Research Institute, McMaster University, Canada) included over 27,000 patients from 32 countries across the world. It involved an international collaboration of committed stroke physicians cardiologists and researchers, keen to build on the landmark INTERHEART study led by Dr Yusuf.

These new results reinforce the fact that action is needed worldwide to control those 10 risk factors – hypertension, lipids, smoking, physical inactivity, abdominal obesity, cardiac causes, diet, alcohol, diabetes mellitus and psychosocial factors – say to the authors.

“The INTERSTROKE study represents an important resource to progress our understanding of the causes of stroke, both in estimating the contribution of known modifiable risk factors for stroke and in identifying and clarifying the role of new ones, such as genetics,” said Dr O’Donnell.

“These results are the completion of eight years of work and, on behalf of the INTERSTROKE group, we are delighted to share them with colleagues from around the world today in this preliminary analysis. We especially look forward to sharing our full data results later this year and continuing to collaborate with colleagues globally to fight the battle against stroke, which is a leading cause of death and disability worldwide,” Dr O’Donnell added.

Published on: May 28, 2014

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  • ArrhythmiaAlliance
  • Stars
  • Anticoagulation Europe
  • Atrial Fibrillation Association

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