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Coffee reduces risk of diabetes

Coffee and caffeine intake may significantly reduce the incidence of type 2 diabetes (T2DM), according to a study published recently in the European Journal of Nutrition.1

Authors identified pertinent studies by a search of PubMed and EMBASE. The fixed- or random-effect pooled measure was selected based on between-study heterogeneity. Dose–response relationship was assessed by restricted cubic spline.

Compared with the lowest level, the pooled relative risk (95 % CI) of T2DM was 0.71 (0.67–0.76) for the highest level of coffee intake (26 articles involving 50,595 T2DM cases and 1,096,647 participants), 0.79 (0.69–0.91) for the highest level of decaffeinated coffee intake (10 articles involving 29,165 T2DM cases and 491,485 participants) and 0.70 (0.65–0.75) for the highest level of caffeine intake (6 articles involving 9,302 T2DM cases and 321,960 participants). The association of coffee, decaffeinated coffee and caffeine intake with T2DM incidence was stronger for women than for men.

A stronger association of coffee intake with T2DM incidence was found for non-smokers and subjects with body mass index \25 kg/m2. Dose–response analysis suggested that incidence of T2DM decreased by 12 % [0.88 (0.86–0.90)] for every 2 cups/day increment in coffee intake, 11 % [0.89 (0.82–0.98)] for every 2 cups/day increment in decaffeinated coffee intake and 14 % [0.86 (0.82–0.91)] for every 200 mg/day increment in caffeine intake.

London GP Dr Sarah Jarvis commented on the implications of this study: “There is growing evidence to suggest that moderate coffee consumption, that’s four to five cups per day, may have a protective effect against the development of T2DM. This new analysis adds to the weight of research in the area and is very relevant to us here in the UK given the high prevalence of T2DM.”

References

1. Jiang X, Zhang D, Jiang W. Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies. Eur J Nutr 2013. http://link.springer.com/article/10.1007/s00394-013-0603-x#

Published on: November 20, 2013

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