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European Society of Cardiology

Clinical Articles, News & Views

Heads up for EHRA – late-breaking clinical trials introduced for the first time

A full programme is promised for the European Heart Rhythm Association (EHRA) EUROPACE 2013 meeting, to be held in Athens, Greece, 23–26 June. The biennial meeting will be for the first time a collaboration between the EHRA and the European Society of Cardiology (ESC) Working Groups on Cardiac Cellular Electrophysiology and e-Cardiology.

The meeting, which spans four days, features over 110 individual sessions, and 18 satellite symposia, is likely to be attended by around 6,000 clinical electro physiologists, general cardiologists, family doctors, basic scientists, computer specialists, cath lab technicians and nurses. Highlights of the late breaking clinical trials include:

  • Gap-AF – AFNET 1 Trial, looking to see whether complete electrical isolation of pulmonary veins is superior to incomplete electrical isolation in patients with drug-refractory paroxysmal atrial fibrillation (AF).
  • SARA trial, comparing the effectiveness and safety of catheter ablation versus anti arrhythmic drug therapy in the treatment of persistent AF.
  • PREFER in AF study which will provide a contemporary snap shot of AF management across Europe.
  • The Leipzig Heart Center AF Ablation Registry monitoring the incidence and risk factors for thromboembolic events after catheter ablation for AF.
  • The CLEPSYDRA study, using algorithms to monitor for early signals of decompensation events in patients with heart failure.
  • RFAVT trial, which will assess mortality for patients treated with Radiofrequency ablations as first line therapy without implantation of an ICD.

Altogether, a record breaking 1084 abstracts have been accepted (out of a total of 1,624 submissions) to be presented at the EHRA EUROPACE 2013. In addition to oral abstract sessions and moderated poster sessions, new for this year will be ‘flash’ abstract presentations where related abstract topics are grouped together. “The idea here is to provide the audience with a lot of information on specific topics, like cardiac resynchronisation therapy or implantable cardioverter defibrillators, in a really short space of time. It should enable delegates to get up to speed on the latest developments quickly,” explained EHRA Scientific Programme Committee chairperson Professor Andreas Goette.

Interesting abstracts to watch out for include:

  • Abstract no 41049, exploring how well electro physiologists are able to estimate quality of life in patients with AF.
  • Abstract no 41271, a study in over 57,000 Danish participants looking at the association of consumption of marine n-3PUFA with AF.
  • Abstract 40935: A case study showing how extensive cola consumption resulted in potassium loss, QT prolongation and a potentially life threatening arrhythmia.
  • Abstract no 40762: exploring ‘mad honey poisoning’ where consumption of honey containing grayanotoxin, from the pollen and nectar of rhododendron species, led to atrioventricular block.
  • Abstract no 40760 suggesting that autoimmune dermatological disorders are associated with increased risk of developing AF.

Professor Goette, said: “This is the first time we’ve ever featured late breaking trials. Journalists will have the opportunity to hear the results of really cutting edge studies, and to learn about the new Guidelines which are likely to have a tremendous impact on the European health care system.”

Another highlight will be the launch of the ESC Clinical Practice Guidelines on Cardiac Pacing & CRT. Professor Michele Brignole, chairman of the Guideline Task Force, said, “These Guidelines, which have been mediated by a team of 70 experts, represent the synthesis of the latest knowledge and state of the art in cardiac pacing and cardiac resynchronisation therapy. They should help place all the studies that have been published over the last six years in context.”

View the scientific programme online at http://media.ne.cision.com/l/myldljij/spo.escardio.org/default.aspx?eevtid=62&showResults=False

Published on: June 20, 2013

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