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Clinical Articles, News & Views

New heart failure treatments on horizon

Dissatisfaction with limited chronic heart failure (CHF) therapies, and the fast-expanding patient population, are encouraging the development of new drug options and superior treatments, according to a new report by GlobalData.1

Demand is growing for new treatment options that can present improved safety and efficacy and unique new molecules that can restore or regenerate impaired cardiac muscle cells, according to the report.

Various pipeline molecules are expected to enter the market within the next few years to improve options for CHF patients, it says, reporting that there are 41 molecules under development in the CHF therapeutics pipeline, of which 78% are First-in-Class (FIC) and 25% are in Phase III.

Several molecules are currently being clinically tested for safety and efficacy in improving cardiac function, and many upcoming drugs include novel mechanisms  for the treatment and management of CHF.  Stem cell therapy may also be capable of improving the CHF treatment pattern, the report says, with the potential to restore cardiac muscle function by regenerating and strengthening heart muscle cells.

GlobalData analysis finds that the global CHF therapeutics market grew at a Compound Annual Growth Rate (CAGR) of 4% from $3,171.3m in 2006 to $3,849.9m in 2011. The report suggests that market will grow at a CAGR of 3.1% during the forecast period, to reach $4,918.4m by 2019.


1 Chronic Heart Failure (CHF) Therapeutics – Pipeline Assessment and Market Forecasts to 2019.  GlobalData 2012.  Available from

Published on: April 18, 2012

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