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Atrial fibrillation, and hypertension
“Hypertension is the most prevalent risk factor leading to the development of atrial fibrillation (AF), the most common arrhythmia” according to Dr I Grundvold, University of Oslo.
In the ATHENA study with dronedarone, for example, 86% of patients had hypertension. It is assumed that this risk increases with increasing BP levels, but it is not known at which level SBP imposes a risk for AF.
He presented data during the 20th European Meeting on Hypertension, in Oslo, recently, from 2014 apparently healthy men aged 45-59 years who were included in the Oslo Ischemia Study, between 1972-75 and who were followed for 35 years. By this time some 272 men (14% of total) had a diagnosis of AF.
The adjusted risk of developing AF was increased by 63% for study participants with baseline BP>128 mmHg (p=0.0003) compared to participants with SBP <128 mmHg. This therefore represented a “strong, independent long-term predictor of AF” according to these investigators.
Published on: June 25, 2010
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